John Mayer’s first serious electric guitar was a Fender Stratocaster Stevie Ray Vaughan Signature model, purchased sometime around 1996. He would use that guitar as his main until around 2003. At that point, he started using a variety of different Stratocasters, including another SRV Strat, a Fender Monterey Stratocaster, and a few different Custom Shop Strats, designed to his own specs.
In 2004 came the “Black one” – the Stratocaster that John designed together with the Fender Custom Shop, to feature his favorite specs and looks. This guitar was most famously used on the “Continuum” album and the following tour. During this same time, Mayer also started using a vintage early 1960 Stratocaster in sunburst, which eventually became his favorite guitar, and the one he still regularly uses nowadays.
In 2015, John decided to switch camps, as he went from Fender to PRS. Together with Paul Reed Smith, he designed his first signature model, the Super Eagle, which he used extensively with the Grateful Dead. A few years later in 2018, PRS introduced the second John Mayer signature guitar called the “Silver Sky”. This second model was based heavily on the Fender Stratocaster but featured significant design and spec changes.
Regarding amps, John went through a few different phases in his career. In the early days, he used Fender combos such as the ’65 Super Reverb and a blonde Vibro-King. In the mid-2000s he began using Two Rock amps almost exclusively. Lastly, more recently in 2015, he began performing with few different PRS amps. He eventually settled on his own signature model, the PRS J-MOD 100.
John also has a pretty big collection of acoustic guitars. His main acoustic guitar throughout the years has been a 2002 Martin OM28-JM – his own signature model from Martin. Next to this one, John had also used a DM3MD model, a limited-edition Dawe Matthews signature guitar, which apparently Mayer had used to record the entirety of the ‘Room for Squares’ album.